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Phabioc

PermeaPlain Barrier

PermeaPlain Barrier

  • 50 pieces per unit
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The classic cellulose membrane for passive diffusion studies

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Based on a permeable regenerated cellulose hydrate, the PermeaPlain Barrier enables the efficient investigation of passive mass transfer of drugs*. Regardless of the substance's polarity, the diffusion of individual drugs through a membrane can be analyzed. This makes it particularly suitable for in vitro release testing (IVRT). Measurements with the barrier are simple, fast, and reproducible. Passive mass transport can be simulated using the PermeaPlain Barrier in a conventional vertical diffusion cell (e.g., Franz cell), side-by-side diffusion cell, or other setups.

*For research purposes only. Not for use in diagnostic procedures.

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What is the PermeaPlain Barrier suitable for?

The PermeaPlain Barrier is used to analyze passive mass transport in in vitro setups. It is particularly suitable for the early screening of potential drugs, regardless of their polarity.

Example applications:

🧫 In vitro release test (IVRT)

🧫 Simulation models in Franz and side-by-side cells

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Why PermeaPlain Barrier?

🧪 Regenerated cellulose membrane – uncoated & pore size of 33nm ± 20nm

💧 Suitable for all substance types – regardless of polarity

🔁 Simple & fast application in classic diffusion cells

📐 Available in 4 standard sizes + custom cuts possible

📏 Cost-effective & reproducible – ideal for screening projects

⚗️ Recommended for side-by-side setups, Franz cells & special cells

Classic diffusion made simple. Without compromise.

  • Typical challenges

    ❌ Complicated in-house production of membranes

    ❌ Low reproducibility with manual preparation

    ❌ Limited size and format variety

  • The solution with PermeaPlain Barrier

    ✅ Uncoated & standardized for reproducible results

    ✅ Available in numerous formats – from 14 to 35 mm Ø

    ✅ On request also available as cut up to 230 × 230 mm

    ✅ Ideal for preclinical screening studies of new drugs
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Frequently Asked Questions

Which membrane base is used?

An uncoated, regenerated cellulose hydrate membrane with a pore size of 33 nm ± 20 nm.

Is the barrier suitable for all fabric types?

Yes – for both lipophilic and hydrophilic substances.

In which formats is the barrier available?

Standard sizes are 14, 17, 25 and 35 mm – also available in custom sizes upon request.

Can I use the barrier in my existing Franz cell?

Yes, it is fully compatible with common diffusion cells.

How is the membrane delivered?

Flat packed, 50 pieces per unit, individually removable.

Tried and tested. Reliable. Scientifically sound.

The PermeaPlain Barrier has been used in preclinical research laboratories for years and is an established tool for standardized diffusion studies. It's ideal for universities, industrial partners, and CROs.

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